Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
Identifieur interne : 001F68 ( Main/Exploration ); précédent : 001F67; suivant : 001F69Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia
Auteurs : Stefanie Gierer ; Heike Hofmann-Winkler ; Waleed H. Albuali ; Stephanie Bertram ; Abdullah M. Al-Rubaish ; Abdullah A. Yousef ; Awatif N. Al-Nafaie ; Amein K. Al-Ali ; Obeid E. Obeid ; Khaled R. Alkharsah ; Stefan PöhlmannSource :
- Emerging Infectious Diseases [ 1080-6040 ] ; 2013.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Anticorps antiviraux (immunologie), Anticorps antiviraux (sang), Anticorps neutralisants (immunologie), Anticorps neutralisants (sang), Arabie saoudite (épidémiologie), Coronavirus (immunologie), Femelle, Humains, Infections à coronavirus (immunologie), Infections à coronavirus (transmission), Infections à coronavirus (épidémiologie), Jeune adulte, Mâle, Études séroépidémiologiques.
- MESH :
- immunologie : Anticorps antiviraux, Anticorps neutralisants, Coronavirus, Infections à coronavirus.
- sang : Anticorps antiviraux, Anticorps neutralisants.
- épidémiologie : Arabie saoudite, Infections à coronavirus.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Jeune adulte, Mâle, Études séroépidémiologiques.
- Wicri :
- geographic : Arabie saoudite.
English descriptors
- KwdEn :
- Adult, Antibodies, Neutralizing (blood), Antibodies, Neutralizing (immunology), Antibodies, Viral (blood), Antibodies, Viral (immunology), Coronavirus (immunology), Coronavirus Infections (epidemiology), Coronavirus Infections (immunology), Coronavirus Infections (transmission), Female, Humans, Male, Middle Aged, Saudi Arabia (epidemiology), Seroepidemiologic Studies, Young Adult.
- MESH :
- chemical , blood : Antibodies, Neutralizing, Antibodies, Viral.
- chemical , immunology : Antibodies, Neutralizing, Antibodies, Viral.
- geographic , epidemiology : Saudi Arabia.
- epidemiology : Coronavirus Infections.
- immunology : Coronavirus, Coronavirus Infections.
- transmission : Coronavirus Infections.
- Adult, Female, Humans, Male, Middle Aged, Seroepidemiologic Studies, Young Adult.
Abstract
We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.
Url:
DOI: 10.3201/eid1912.130701
PubMed: 24274664
PubMed Central: 3840893
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>We used a lentiviral vector bearing the viral spike protein to detect neutralizing antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV) in persons from the Eastern Province of Saudi Arabia. None of the 268 samples tested displayed neutralizing activity, which suggests that MERS-CoV infections in humans are infrequent in this province.</p>
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